While dermaplaning and microdermabrasion can both target rough, dull skin, the two treatments are very different. Microdermabrasion uses a gentle sanding motion to remove dead skin cells, while dermaplaning gently scrapes dead skin cells away. Dermaplaning also addresses facial hairs, while microdermabrasion does not. Dermaplaning can be done on sensitive skin that could be irritated by microdermabrasion.